Puromycin, 10 mg/mL_Shanghai BasalMedia Technologies Co.,LTD

Puromycin, 10 mg/mL

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Catalog Number：S250J0

Size：1 mL

Product Description

Puromycin is an aminonucleoside antibiotic produced by fermentation and metabolism of Streptomyces alboniger. The inhibition of protein synthesis kills gram-positive bacteria as well as various animal and insect cells, it is also applicable for E.Coli under certain circumstances. As a analogue to the 3’ terminal of Aminoacyl -tRNA molecule, puromycin can bind to the A site of ribosome and be added to the extended peptide chain. However, puromycin will no longer react after binding to the A site resulting in premature termination of protein synthesis and releases premature peptides from the C end containing puromycin.
Resistance to puromycin is conferred by the puromycin N-acetyl-transferase gene (pac) from Streptomyces. Genetic engineering research uses pac gene derived from puromycin producing bacteria Streptomyces alboniger.
Puromycin is commonly used for screening and maintaining the cultivation of stable transfection mammalian cells containing pac gene. The general application of puromycin in the selection of stable cell strains is related to the characteristics of lentivirus vectors, most commercial lentivirus vectors carrying pac genes nowadays. Under certain circumstances, puromycin can also be used to screen and transform E.Coli carrying pac gene.
The product is prepared using water-for-injection.
This product is only used for scientific research and production, tissue and cell culture in vitro. It is prohibited for clinical use.

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Products from Shanghai BasalMedia Technologies Co.,LTD are all manufactured in cGMP-compliant facilities. Shanghai BasalMedia Technologies Co.,LTD is certified with ISO9001:2015 and ISO13485:2016 quality system standards.

Manufacturing Assurance

We have been committed to adopting modern management models to make all production and operation activities, including safety production management, scientific, standardized and legalized. It comprehensively promotes the occupational health and safety management system in a scientific way to create a healthy, safe and friendly working environment for every employee of BasalMedia Technologies. We have passed the ISO45001:2018 Occupational Health and Safety Management System Certification and ISO14001:2015 Environmental Management System Certification.

Catalog Number	Size	Price (CNY)	Availability
S250J0	1 mL	400.00

Specifications

Shelf Life	24 months
Storage Conditions	-30～-5 ℃